Summary: Long-lived reservoirs of persistent HIV are a major barrier to a cure.CD4+ hematopoietic stem and 8.31/8GB progenitor cells (HSPCs) have the capacity for lifelong survival, self-renewal, and the generation of daughter cells.Recent evidence shows that they are also susceptible to HIV infection in vitro and in vivo.Whether HSPCs harbor infec
Abstract The discovery of secondary metabolites from marine microorganisms is beset by numerous challenges including difficulties cultivating and subsequently eliciting expression of biosynthetic genes from marine microbes in the laboratory.In this paper, we describe a method of culturing three species from the marine bacterial genus Pseudoalteromo
Over the last two decades, students and teachers, across educational levels and disciplines, have been subject to a variety of school reform efforts.Nevertheless, some instructional practices, such as portfolio assessment, persist and grow in popularity even in the midst of changing educational reform goals and shifting priorities.Teacher education
Background Awake craniotomy is a well-tolerated procedure for the resection of brain tumors residing within or close to the eloquent cortical areas.Monitored anesthesia care (MAC) Apparel is a dominant anesthetic approach for awake craniotomy; however, it is associated with inherent challenges such as desaturation and hypercapnia, which may lead to